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The Innate Immunity Signal Transduction in Human Leukocytes is a research study to determine the response of immune cells from the bloodstream.

Innate immunity is the process by which white blood cells and other parts of the immune system sense and respond to potential infections by causing an inflammation.

NIEHS Studies - Open for Recruitment

NIEHS researchers theorize that changes in the surface proteins of cells called receptors may predispose people to diseases, such as heart disease, arthritis, and diabetes.

Asthma patients seem to be more prone to viral infections, and NIEHS scientists believe that the cells that line these patients' airways, cause this result by overproducing TGF-beta1, a protein that promotes viral growth.

Researchers are interested in developing a registry protocol to obtain biologic and environmental samples anonymously from adult volunteers for use in laboratory tests and studies.

The gene p53 suppresses cancer and inflammation in the body, and NIEHS investigators speculate that changes in p53 lead to changes in inflammation and the ability to repair DNA damage.

The Personalized Environment and Genes Study (PEGS), formerly the Environmental Polymorphisms Registry or EPR, is a long-term research project to collect health, exposure, medical and genetic data from a diverse group of people in North Carolina in the United States.

According to the Centers for Disease Control and Prevention, cigarette smoking causes more than 480,000 deaths each year in the United States, which translates to causing nearly one of every five deaths.

Many women develop irregular menstrual cycles which may make it difficult to become pregnant and increase the risk of osteoporosis.

The goal of the NHALES Study is to help scientists understand how bacteria and other factors in the environment affect people who have moderate to severe asthma.

This study evaluates subjects with adult- and childhood-onset myositis to learn more about their causes, and the immune system changes and medical problems associated with them.

Girls seem to be going through puberty a lot earlier these days and doctors think it may be related to body weight. This study researches whether overweight girls go through puberty earlier than normal weight girls.

This study will find out more about calcinosis, the development of calcium deposits in various parts of the body, in people with dermatomyositis (DM) and juvenile dermatomyositis (JDM). Calcinosis can be painful and cause disabilities and other problems, so scientists want to find treatments for it.

A study conducted by NIEHS where moms can help their daughters prepare for puberty and demystify a girl’s first period.